Nalfurafine is a G-protein biased agonist having significantly greater bias at the human than rodent form of the kappa opioid receptor - ScienceDirect
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists
Molecular mechanisms of opioid tolerance: From opioid receptors to inflammatory mediators (Review)
IJMS | Free Full-Text | Three-Dimensional Structural Insights Have Revealed the Distinct Binding Interactions of Agonists, Partial Agonists, and Antagonists with the µ Opioid Receptor
IJMS | Free Full-Text | Is p38 MAPK Associated to Drugs of Abuse-Induced Abnormal Behaviors?
Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons | Journal of Neuroscience
Chronic Kappa opioid receptor activation modulates NR2B: Implication in treatment resistant depression – topic of research paper in Clinical medicine. Download scholarly article PDF and read for free on CyberLeninka open science
κ-opioid receptor - Wikipedia
Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect
Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination | Nature Communications
Dopaminergic Cellular and Circuit Contributions to Kappa Opioid Receptor Mediated Aversion
Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects
Enhancing Remyelination through a Novel Opioid-Receptor Pathway | Journal of Neuroscience
Kappa opioid receptor (KOR) activation study. A): G protein activation... | Download Scientific Diagram
Opioids As Modulators of Cell Death and Survival—Unraveling Mechanisms and Revealing New Indications | Pharmacological Reviews
Frontiers | Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic Targets: Recent Progress and Future Perspective
Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System
Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion
Reactive oxygen species (ROS) generation is stimulated by κ opioid receptor activation through phosphorylated c-Jun N-terminal kinase and inhibited by p38 mitogen-activated protein kinase (MAPK) activation - ScienceDirect
Frontiers | Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry
