Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist
RTI International's JDTic Helps Scientists Uncover Structure of the Kappa Opioid Receptor | RTI
Kappa opioid receptor labeled with Tb (HTRF transiently expressing cells)
Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain | Journal of Neuroscience
The blocking of kappa‐opioid receptor reverses the changes in dorsolateral striatum dopamine dynamics during the amphetamine sensitization - Azocar - 2019 - Journal of Neurochemistry - Wiley Online Library
RCSB PDB - 6B73: Crystal Structure of a nanobody-stabilized active state of the kappa-opioid receptor
κ-Opioid Receptor (KOP) | 7TM Antibodies
Structure of the human κ-opioid receptor in complex with JDTic | Nature
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect
Molecules | Free Full-Text | A Structure-Activity Relationship Comparison of Imidazodiazepines Binding at Kappa, Mu, and Delta Opioid Receptors and the GABAA Receptor
Discovery of κ Opioid Receptor (KOR)-Selective d-Tetrapeptides with Improved In Vivo Antinociceptive Effect after Peripheral Administration | ACS Medicinal Chemistry Letters
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience
Study targets kappa opioid receptor to develop more effective drugs for pain management | Anesthesiology | Washington University School of Medicine in St. Louis
Molecular mechanism of biased signaling at the kappa opioid receptor | Nature Communications
Frontiers | Agonist-Promoted Phosphorylation and Internalization of the Kappa Opioid Receptor in Mouse Brains: Lack of Connection With Conditioned Place Aversion
RCSB PDB - 8DZR: GR89,696 bound Kappa Opioid Receptor in complex with gustducin
Frontiers | Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain
Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects